Wine tasting

Biddle Ranch Vineyard - Link here
Chamisal Vineyards - Link here
Baileyana - Link here
Talley Vineyards - Link here 
Edna Valley Vineyard - Link here
Tolosa Winery - Link here
And (250+) more - SLO Wine Tasting Map

local breweries

Firestone Walker Brewing Company- Link here
Figueroa Mountain Brewing Company - Link here
The Libertine Brewing Company - Link here
Tap It Brewing Co. - Link here
SLO Brew -The Rock - Link here
BarrelHouse Brewing Company - Link here

Hiking and adventures

Bishop Peak - Link here
Pismo Preserve - Link here
Montaña De Oro State Park - Link here
Madonna Mountain - Link here
Ziplining - Link here
Surfing - Link here
Kayaking - Link here
Deep Sea Fishing - Link here
Pismo Oceano Dunes (ATV Riding) - Link here

Sights and Landmarks

Mission San Luis Obispo de Tolosa - Link here
Madonna Inn - Link here
Avila Valley Barn - Link here
Hearst Castle - Link here
Downtown Farmers' Market (Thursday Night) - Link here
Avila Beach Farmers' Market (Friday Night) - Link here